هيدروكلوريد البوبرينورفين
| Kind | API |
|---|---|
| Class | Opioid — partial mu agonist / kappa antagonist |
| Synonyms | Buprenorphine HCl, Buprenorphini hydrochloridum |
| Common uses / forms | Sublingual tablets/films (often with naloxone), transdermal patch (base), injection; pain and opioid-use-disorder maintenance |
| Properties | Semi-synthetic thebaine derivative; very high receptor affinity, partial agonist with ceiling effect; high first-pass so non-oral routes; Schedule III controlled; potent (containment) |
| Compendia | USP, EP, BP |
| Sourcing origins | UK, EU, India |
| Dominant inbound route | EU |
| Indicative price band | $$$$ (> $1000 / kg) |
| Indicative lead time | long (80–120+ days) |
| Notes | Thebaine-derived controlled narcotic made by only a few licensed potent-API producers; high-containment; OUD formulations carry program/REMS constraints in some markets. |
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Cite as: AUPAM Experts' Office, Buprenorphine Hydrochloride — sourcing profile (API) — AUPAM Data Bank, retrieved 2026-08-31, https://aupameo.org/datasets/databank/a-buprenorphine-hydrochloride.html