إيتراكونازول
| Kind | API |
|---|---|
| Class | Antifungal — triazole (systemic) |
| Synonyms | Itraconazolum, R 51211 |
| Common uses / forms | Systemic antifungal; pelletized capsules, cyclodextrin oral solution, IV; onychomycosis, aspergillosis, histoplasmosis, blastomycosis |
| Properties | BCS Class II; weak base, extremely poorly water-soluble; highly lipophilic (logP ~5.7); oral bioavailability depends on amorphous solid dispersion / pellet coating and gastric pH |
| Compendia | USP, EP, BP |
| Sourcing origins | India, China, EU |
| Dominant inbound route | Hormuz |
| Indicative price band | $$$ ($100–1000 / kg) |
| Indicative lead time | medium (50–80 days) |
| Notes | Bioavailability is formulation-critical; amorphous solid-dispersion and bead-coating know-how drive quality differentiation between sources |
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Cite as: AUPAM Experts' Office, Itraconazole — sourcing profile (API) — AUPAM Data Bank, retrieved 2026-08-31, https://aupameo.org/datasets/databank/a-itraconazole.html