كيتوكونازول
| Kind | API |
|---|---|
| Class | Antifungal — imidazole |
| Synonyms | Ketoconazolum, R 41400 |
| Common uses / forms | Topical creams and shampoos (1–2%); oral tablets now restricted; dermatophytoses, seborrheic dermatitis, pityriasis versicolor |
| Properties | BCS Class II; weak dibasic base; poorly water-soluble with pH-dependent dissolution requiring an acidic gastric environment |
| Compendia | USP, EP, BP, IP |
| Sourcing origins | China, India |
| Dominant inbound route | Hormuz |
| Indicative price band | $$ ($10–100 / kg) |
| Indicative lead time | medium (50–80 days) |
| Notes | Systemic/oral use curtailed by regulators over hepatotoxicity; topical demand now dominates; mature commodity API with many sources |
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Cite as: AUPAM Experts' Office, Ketoconazole — sourcing profile (API) — AUPAM Data Bank, retrieved 2026-08-31, https://aupameo.org/datasets/databank/a-ketoconazole.html