ميثوتريكسات
| Kind | API |
|---|---|
| Class | Antineoplastic — antimetabolite (antifolate) |
| Synonyms | MTX, Amethopterin, Methotrexate sodium |
| Common uses / forms | Injectable vials & pre-filled syringes and oral tablets; high-dose oncology plus low-dose immunology use |
| Properties | BCS Class III (high solubility, low permeability); weak polyprotic acid with pH-dependent solubility; sodium salt is hygroscopic and photosensitive |
| Compendia | USP, EP, BP, JP, IP |
| Sourcing origins | China, India, EU |
| Dominant inbound route | Hormuz |
| Indicative price band | $$$ ($100–1000 / kg) |
| Indicative lead time | medium (50–80 days) |
| Notes | Cytotoxic — needs contained/dedicated facilities; injectable grade requires low endotoxin; tight control of related antifolate impurities. |
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Cite as: AUPAM Experts' Office, Methotrexate — sourcing profile (API) — AUPAM Data Bank, retrieved 2026-08-31, https://aupameo.org/datasets/databank/a-methotrexate.html