تيوتروبيوم بروميد
| Kind | API |
|---|---|
| Class | Bronchodilator — long-acting muscarinic antagonist (LAMA) |
| Synonyms | Ba 679 BR, tiotropium bromide monohydrate, Spiriva |
| Common uses / forms | Inhalation powder (HandiHaler capsules ~18 µg) and Respimat soft-mist (2.5 µg/actuation); COPD, asthma maintenance |
| Properties | Quaternary-ammonium anticholinergic; extremely low unit dose; inhalation-grade micronization (~1–5 µm) with tight particle-size distribution and polymorph/monohydrate control mandatory |
| Compendia | USP |
| Sourcing origins | India, China, EU |
| Dominant inbound route | Hormuz |
| Indicative price band | $$$$ (> $1000 / kg) |
| Indicative lead time | long (80–120+ days) |
| Notes | Inhalation-grade micronization and PSD control limit the pool of truly qualified suppliers; Boehringer originator plus device (Respimat) complexity; crystalline-form identity is critical |
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Cite as: AUPAM Experts' Office, Tiotropium bromide — sourcing profile (API) — AUPAM Data Bank, retrieved 2026-08-31, https://aupameo.org/datasets/databank/a-tiotropium-bromide.html