بولي سوربات 80
| Kind | Excipient |
|---|---|
| Class | Surfactants & emulsifiers — nonionic (polyoxyethylene sorbitan ester) |
| Synonyms | Tween 80, Polyoxyethylene (20) sorbitan monooleate, POE (20) sorbitan monooleate, E433 |
| Common uses / forms | Emulsifier, solubilizer and wetting agent; surfactant/stabilizer in biologic and vaccine formulations; injectables, oral liquids, topicals. |
| Properties | Nonionic surfactant, HLB ~15; viscous amber liquid; oxidation-prone (peroxide/formaldehyde formation). Grades differ by fatty-acid spec and purity — super-refined / high-purity (low-peroxide) grade required for parenteral and protein products. |
| Compendia | USP, EP, BP, JP |
| Sourcing origins | China, EU, USA, Japan |
| Dominant inbound route | Hormuz |
| Indicative price band | $$ ($10–100 / kg) |
| Indicative lead time | medium (50–80 days) |
| Notes | Peroxide/carbonyl control is the key quality risk for biologics; specify super-refined parenteral grade and vegetable-origin oleic acid where required. JP carries a Polysorbate 80 monograph (verified). |
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Cite as: AUPAM Experts' Office, Polysorbate 80 — sourcing profile (Excipient) — AUPAM Data Bank, retrieved 2026-08-31, https://aupameo.org/datasets/databank/e-polysorbate-80.html