تريهالوز
| Kind | Excipient |
|---|---|
| Class | Buffers, tonicity & sugars — sugar / lyoprotectant |
| Synonyms | Trehalose dihydrate, Alpha,alpha-trehalose, Mycose |
| Common uses / forms | Lyo/cryoprotectant and stabilizer for biologics (mAbs, vaccines, proteins); tonicity agent |
| Properties | White crystalline powder (dihydrate); freely soluble in water; non-reducing disaccharide; high glass-transition temperature; MW 378.33 (dihydrate) |
| Compendia | USP, EP |
| Sourcing origins | Japan, China |
| Dominant inbound route | Hormuz |
| Indicative price band | $$$ ($100–1000 / kg) |
| Indicative lead time | medium (50–80 days) |
| Supply flag | Single-source — concentrated supplier base; plan a second source |
| Notes | Pharma injectable/lyoprotectant grade concentrated among very few qualified producers (Hayashibara/Nagase Japan; Pfanstiehl/Ferro); food grade more widely available; low-endotoxin, non-reducing so amine-safe |
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Cite as: AUPAM Experts' Office, Trehalose — sourcing profile (Excipient) — AUPAM Data Bank, retrieved 2026-08-31, https://aupameo.org/datasets/databank/e-trehalose.html