A key drug or excipient is in shortage — how do I mitigate and find an alternative source?
دواء أو سواغ رئيسي في حالة نقص · كيف أخفّف الأثر وأجد مصدرًا بديلًا؟
Why this happens
Shortages cascade from single sources, long lead times, and no early-warning signal — by the time production stops, the qualified alternatives are months away.
تتسلسل حالات النقص من المصادر الوحيدة، وطول مدد التوريد، وغياب الإنذار المبكّر · وحين يتوقّف الإنتاج تكون البدائل المؤهّلة على بُعد أشهر.
What to do, step by step
Assess criticality and cover: how many days of stock, and is the item single-sourced?
Identify pre-qualified alternatives (CEP/DMF holders for APIs; compendial-grade alternates for excipients) and start qualification now.
Apply mitigation: safety-stock policy, allocation, and — for a compendial excipient — a like-for-like functional equivalence check.
Institutionalise dual sourcing and subscribe to a disruption-signal feed so the next event is seen early.
قيّم الحرجية والتغطية: كم يومًا من المخزون؟ وهل الصنف أحادي المصدر؟
Cite as: AUPAM Experts' Office, A key drug or excipient is in shortage — how do I mitigate and find an alternative source? — AUPAM Solutions Bank, retrieved 2026-08-31, https://aupameo.org/datasets/solutions/q11-a-key-drug-or-excipient-is-in-shortage-how-do-i-mitigat.html