بولوكسامير 188
| Kind | Excipient |
|---|---|
| Class | Surfactants & emulsifiers — nonionic (PEO-PPO-PEO block copolymer) |
| Synonyms | Kolliphor P188, Lutrol F68, Pluronic F68, Poloxalkol |
| Common uses / forms | Wetting/solubilizing agent, emulsifier, shear-protectant surfactant in biologics and cell culture; oral, parenteral and topical dosage forms. |
| Properties | Nonionic triblock copolymer (~80% PEO), average MW ~8,400; HLB >24; white waxy solid/prills, freely water-soluble. Low-toxicity, well tolerated parenterally. |
| Compendia | USP, EP, BP |
| Sourcing origins | EU, USA, China |
| Dominant inbound route | EU |
| Indicative price band | $$ ($10–100 / kg) |
| Indicative lead time | medium (50–80 days) |
| Notes | Pharma-grade market led by BASF (Kolliphor/Lutrol) but multiple GMP suppliers exist, so not sole-source; qualify grade, EO/PO ratio and residual-monomer limits for parenteral use. |
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Cite as: AUPAM Experts' Office, Poloxamer 188 — sourcing profile (Excipient) — AUPAM Data Bank, retrieved 2026-08-31, https://aupameo.org/datasets/databank/e-poloxamer-188.html