بولوكسامير 407
| Kind | Excipient |
|---|---|
| Class | Surfactants & emulsifiers — nonionic (PEO-PPO-PEO block copolymer) |
| Synonyms | Kolliphor P407, Lutrol F127, Pluronic F127 |
| Common uses / forms | Thermoreversible gelling agent, solubilizer, emulsifier and controlled-release matrix; in-situ gels, ophthalmic, topical and injectable depot systems. |
| Properties | Nonionic triblock copolymer (~70% PEO), average MW ~12,600; white waxy solid; concentrated aqueous solutions gel on warming to body temperature (thermogelation) — the defining functional property. |
| Compendia | USP, EP, BP |
| Sourcing origins | EU, USA, China |
| Dominant inbound route | EU |
| Indicative price band | $$ ($10–100 / kg) |
| Indicative lead time | medium (50–80 days) |
| Notes | BASF-led pharma supply but not sole-source; gelation temperature is grade/concentration sensitive — specify functionality-related characteristics for in-situ gel products. |
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Cite as: AUPAM Experts' Office, Poloxamer 407 — sourcing profile (Excipient) — AUPAM Data Bank, retrieved 2026-08-31, https://aupameo.org/datasets/databank/e-poloxamer-407.html